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c elegan more lipid lifespan Figure 2 from Lessons from C. elegans: Signaling pathways for longevity Lifespan-regulating genes in C. elegans
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Because the substrate-binding site does not overlap with this acidic site, it was proposed that protonation of the critical aspartate (D41) by extracellular protons causes TM1 bending, the collapse of the N-lobe cavity and concomitant extrusion of the substrate into the periplasm, and eventually the return to the inward-open state

[DOI] [PubMed] [Google Scholar] Michels A

110 ParameyongA.GovitrapongP.ChetsawangB
