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When comparing three astrocytic PET tracers ([ 11 C] d-l-deprenyl, [ 18 F] SMBT-1 and [ 11 C] BU99008), some differences in the sensitivity to pick up changes in astrogliosis during the development of AD were noted

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Conversely, animals who received NSI-189 orally for 4 weeks, following the radiation exposure, showed levels of novel environment exploration on par with control animals