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4-trimethylaminobutyraldehyde is then dehydrogenated by 4-trimethylaminobutanal dehydrogenase (TMABA-DH) results in the formation of 4-trimethylammoniobutanoate, also known as butyrobetaine

Vari C, Osz B, Perian M, Mruteri M, Miklos A, Bosa P, Tero-Vescan A

doi: 10.1073/pnas.93.18.9799, 185

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In this respect, an interesting study conducted on immortalized human microglia cells (CVCL_5G94) highlighted how ATRAs can increase the heat shock protein 90 (Hsp90) expression on the surface of these cells, causing an increase in the amount of endocytosed and consequently eliminated tau protein (25)

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