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Clinical trial NCT04050670 examined tirzepatide absorption at different sites and found something interesting

This may be a good alternative for people who want a medication that works like Wegovy but dont want to take an injection

Natriuretic Peptides Atrial Natriuretic Peptide (ANP) and B-type natriuretic peptide (BNP), the main natriuresis hormones, are synthesized in cardiac tissue in response to stretching that occurs with increases in blood volume and function to decrease extracellular fluid volume and increase renal sodium excretion (108)

Int J Lab Hematol

Draw 0.3mL per dose instead of 0.25mL to maintain 5mg dosing

These findings suggest that the cardiovascular benefits observed in the study were more closely associated with attained semaglutide dose than with weight loss alone