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The presence of gyri can significantly affect the movement of the brain within the skull, and lead to more brain deformation (Finnie, 2001

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Moreover, plain radiographs were used to determine the grade of intervertebral disc degeneration in the present study, impeding the assessment of facet joint degeneration and potentially limiting the comparability with in vivo studies using magnetic resonance imaging, as gradings of disc degeneration from X-rays and magnetic resonance images were found to differently predict the flexibility of the lumbar spine 43