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Firstly, the methodological quality of included studies was less than optimal, so we were not able to exclude the potential risk of bias in these trials

After the capture of Forts Clinton and Montgomery, near the lower entrance to the Highlands, in 1777, and the abandonment of Fort Constitution by the Americans a few days afterward, public attention was directed to the importance of other and stronger fortifications in that vicinity

Ishikawa T, Abe S, Watanabe T, et al

Ezell 1961:110

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The current work provides the first identification of certain PD-type biochemical changes in neurons of patients carrying a triplication of the S gene