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These abnormally large red blood cells, known as megaloblasts, simply can't carry oxygen as efficiently as healthy, normal-sized ones

Hence, many attempts have been made to find drugs that can control nonpolymerizing fetal hemoglobin [88]

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In some cases, especially for individuals with digestive issues or malabsorption conditions, the efficiency of oral supplementation can be severely compromised, leading to nutrient deficiencies despite adequate intake