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127 HK deficiency (OMIM 235700)* is a rare, recessively inherited disease with chronic nonspherocytic hemolytic anemia as the predominant clinical feature

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There is no evidence that doses above 500mcg produce proportionally better results, and clinical trials using 1mg daily did not dramatically outperform lower doses

This review investigates the anti-inflammatory role of DMF in oxidative stress and its effect by reducing ROS through glutathione modulation

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[DOI] [PubMed] [Google Scholar] Morell S, Follmann H, De Tullio M, Hberlein I
