glutathione reduced vs oxidized states Redox cycle. Abbreviations. GSSG: Glutathione, Glutathione in the Brain |

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doi: 10.1007/s40262-017-0532-6

Glutathione is a small molecule (a tripeptide of the amino acids glutamate, cysteine, and glycine) that the body produces in every cell

A 2021 review published in Nutrients found that GLP-1 receptor agonist use was associated with reduced dietary intake of multiple micronutrients including B12, particularly in patients following calorie-restricted eating patterns, supporting the rationale for monitoring B12 status during treatment even in patients without pre-existing deficiency risk factors

However, a significant number of patients either do not respond to these treatments or eventually, these lose their effectiveness, indicating a need for alternative therapies (2)

In addition, NPD4928 does not show any cytotoxicity against the HCT116 cell line