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These functional changes are based on a fundamental immunometabolic reprogramming, resulting in enhanced mitochondrial oxidative metabolism, thus conferring an increased immunometabolic capacity to human T cells

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AAPS PharmSciTech 24 (4), 98
Guillin, O

doi: 10.3390/antiox11081469

The steady state volume of distribution, Vdss , was calculated from Vdss = dose.MRT/AUCi.v