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An important role of GSSG in the NFkappaB activating signal cascade is suggested by the facts that the potent NFkB inducer, tetradecanoyl phorbol acetate, increases intracellular GSSG levels and GSSG/GSH ratios

Askarpour, M., Hadi, A., Symonds, M., Miraghajani, M., Miraghajani, M., Sadeghi, O., Sheikhi, A., & Ghaedi, E

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[282] The US Food and Drug Administration (FDA) and the Centers for Disease Control and Prevention (CDC) authorized the use of an additional mRNA vaccine dose for immunocompromised individuals at that time