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& Vina, J

Epilepsia 44 , 847851

Long-term HFD consumption increased hepatic IKK- glutathionylation and NF-B suppression The mechanistic investigations in our cell culture studies provided evidence suggesting that intracellular GSSG accumulation sensitizes hepatocytes to TNF cytotoxicity via the induction of IKK- glutathionylation, leading to reduced IKK- phosphorylation and subsequent NF-B suppression

T.WadeM.NomikosG

Mechanistically, a recent study demonstrated that chronic restraint stress worsens dextran sodium sulfate-induced colitis via an HPA axis-dependent pathway

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