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In this study, we conducted single-cell RNA sequencing (scRNA-seq) analysis of kidney samples, revealing the occurrence of ferroptosis in renal tubular cells of an oxalate-induced AKI mouse model, which was confirmed in subsequent in vitro experiments
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We conclude that intracellular pyruvate, or other -ketoacids, whose endogenous concentration is controlled by metabolism, have little role in H2O2 clearance
