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10.1038/s41598-017-18596-0 Sci Rep

While GLP-1 and GIP receptor agonists are highly effective for initiating caloric deficits, human metabolism is highly adaptive

Cardiac adverse events, including bradycardia, bradyarrhythmia, and atrioventricular conduction delays, were noted when treatment was started without dose titration

Solubility Parameter Approach The functional group contribution method was used to determine the Hansen solubility parameter for the drug and carriers [5]

Not perfect, mind you, but the difference was night and day compared to where I started

230 These data suggest bempedoic acid is safe and effective and can be combined with other drug therapies to support healthy LDL cholesterol levels and promote cardiovascular health