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Other things that deplete glutathione include alcohol, recreational drug use, a fructose rich diet, the natural aging process, prolonged fasting (24 hours or longer), and anything that causes increases in oxidative stress

It has been found that the thioredoxin reductase system and glutathione peroxidase system play an important role in cellular oxidative stress defense (Lee et al., 2012

But even if you and your veterinarian are able to get the underlying problem under control, the symptoms may not completely resolve because if left untreated, cobalamin deficiency causes vomiting, diarrhea, and weight loss

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Proc R Soc Lond B Biol Sci