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FIGURE 9 ACs in endothelial cells play a role in vascular permeability

Instead, a sophisticated pathway for specific uptake and transport of this molecule has evolved

The reaction between DSF and Cu ions forms a copper diethyldithiocarbamate complex (Cu(DDC) 2 also known as CuET) which is the active, potent anticancer ingredient through inhibition of NF-B and ubiquitin-proteasome system as well as alteration of the intracellular reactive oxygen species (ROS)

JAMA Neurol (2023) 80(4):40414

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Merad M, Martin JC (2020) Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages