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10.18632/oncotarget.1862 62 LiuP.WuD.DuanJ.XiaoH.ZhouY.ZhaoL.et al (2020)

Cells and extracellular spaces are exposed to a large variety of reactive stimuli from both exogenous and endogenous sources

These include the induction of elastase and MMPs synthesis, the regulation of growth factors and signaling pathways, and the modulation of epigenetic marks that influence gene expression

A recent study also highlighted positive associations between vitamin B 12 and enhanced sperm motility, sperm count, and DNA integrity

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Diabetes has been widely associated with oxidative damage, increased GSSG/GSH ratio and decreased GSH content in different tissues [67,68]
