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Inhibition of aldose reductase prevents angiogenesis in vitro and in vivo

In preclinical models across muscle, tendon, ligament, and bone injury models, it improved functional, structural, and biomechanical outcomes

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With regard to protein synthesis , it is of interest to note that certain disorders due to genetic abnormalities cause impairment of ribosome structure and function and have been named ribosomopathies

Hedlund GL, Longo N, Pasquali M

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