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These reactive molecules have a signaling function, modifying the Keap1 protein, which leads to Nrf2 activation (124)

Try to keep in mind this is a medicalease definition that means something different than what you expect it to mean in plain English

2020;370:m3095]
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Attenuation of neuromotor deficits by natural antioxidants of Decalepis hamiltonii in transgenic Drosophila model of Parkinsons disease

GCEE may react directly with ROS due to the cysteine residue and/or increase GSH, which can protect against ROS and nucleophilic compounds
