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Methylcobalamin, or vitamin B12, is a B-vitamin

Additional risk factors include: Chronic kidney disease : Reduced renal clearance may impair B12 excretion Liver disease : Hepatic dysfunction can disrupt B12 metabolism and storage Myeloproliferative disorders : Certain blood cancers increase B12-binding proteins Concurrent medication use : Some drugs may interact with B12 metabolism, including metformin, proton pump inhibitors, and H2 antagonists Patients with these conditions should have B12 supplementation carefully monitored by their healthcare team

Potential interactions with drugs metabolized by methyltransferases should be considered

Folic acid should be used with extreme caution in patients with undiagnosed anemia

Maintaining healthy levels of B12 in the body prevents anemia