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Several studies have demonstrated that NAD + metabolism is involved in neuronal function and in the pathophysiology of neurodegenerative diseases (Hikosaka et al., 2019) and that NAD + levels in tissues can produce beneficial therapeutical effects in this type of diseases (Kulikova et al., 2018)

The resuspended bacteria were lysed by ultrasonication on ice (four 5-min sessions with 30% amplitude, 2.0 s pulse on, 2.0 s pulse off, interspersed with 1-min pauses)
Stress-induced release of prolactin: blockade by dexamethasone and naloxone may indicate beta-endorphin mediation

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