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In addition to mutation and overexpression of the biosynthetic genes and/or riboswitch sequences in the selected strains, the catalytic initiator of 5aminolevulinic acid (ALA), DMB, and cobalt ions were all introduced to enhance cobalamin production (NguyenVo et al., 2018)
On the contrary, non-epithelial malignancies and sarcomas rarely expressed GT
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