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Raising the GSH levels improved liver function during abstinence [57]
A critical maladaptation is the dysregulation of ion channels, specifically the pathological upregulation and altered trafficking of voltagegated sodium channels (e.g., Nav1.3, Nav1.7, Nav1.8) and Ntype calcium channels [54, 57, 58, 71]
Long-term safety depends on baseline health status, biomarker monitoring, and individual tolerance
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Cell Host Microbe (2011) 9:35561
