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Biological functions and subcellular localization data were sourced from the UniProt Knowledgebase ( 36
10.1111/j.1528-1157.1993.tb02419.x
This suggests that the decoupling observed in P301L SH-SY5Y cells may be linked to the overexpression of P301Ltau
The cytosol is important for Cd detoxification in these cells since the first contact with metals after uptake into cells occurs here and it is the major compartment for PC synthesis [173]
Because GSH itself is easily oxidized by some substances, it can protect the sulfhydryl groups in many proteins and enzymes from being oxidized by harmful substances in the body, to ensure the normal play of molecular physiological functions such as proteins and enzymes
Therefore, the balance of amino acid neurotransmitter metabolism is essential in order to maintain a perfect neuronal functioning
