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Our findings are consistent with other studies showing that acute neuroendocrine stressors suppress antioxidant defenses in the brain of zebrafish 13 as well as in rodents showing a decrease in antioxidant levels in both plasma and the brain 55,59,60

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In addition, we observed that the RP cells were strikingly sensitive to cuproptosis induction with ES and Cu, in comparison with the starting lines
Selenium is an essential trace element that supports antioxidant defense through enzymes like glutathione peroxidase [54]

The efficiency of this reaction is associated with the bond dissociation enthalpy of the OH bond
