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Various neutrophil-derived cytokines and granular proteins also influence vascular permeability and endothelial dysfunction

This suggests that dietary fiber interventions can modulate microbial pathways relevant to TMAO metabolism, reinforcing the beneficial role of fiber-rich diets

One study showed that the p.Arg294 mutation in younger patients is associated with greater disturbances in initiating and maintaining sleep (23)

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Orexin receptors: pharmacology and therapeutic opportunities