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Immunol Res (2006) 35(12):12736.10.1385/IR:35:1:127 149 SaxtonTMHenkemeyerMGascaSShenRRossiDJShalabyFet alAbnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2

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The receptor manifests the most pronounced affinity to IGF-1 and a two-fold lower one to IGF-2 (17,68,74)

This subtype affects about 11% of rosacea patients

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