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Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11(9):e2305363 Yan Y, Lu A, Dou Y, Zhang Z, Wang XY, Zhai L, Ai LY, Du MZ, Jiang LX, Zhu YJ, Shi YJ, Liu XY, Jiang D, Wang JC (2023) Nanomedicines reprogram synovial macrophages by scavenging nitric oxide and silencing CA9 in progressive osteoarthritis

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While these findings strongly support macrophage-targeted repurposing strategies in colorectal cancer, similar immunosuppressive mechanisms are also prominent in other highly lethal malignancies

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