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Description

H., Jeong, E

The liver, the largest solid organ in the human body, is an essential part of the digestive system, responsible for blood detoxification, nutrient metabolization, and immune function regulation

Despite methodological differences across studies, such as delivery routes (intravenous, local, or intranasal), donor mitochondrial sources, and animal models, redundant beneficial effects are consistently reported, including the restoration of mitochondrial function, limitation of cellular damage, reduction of ROS, and enhancement of antioxidant responses

Compared to the vehicle and GPE + GH groups, GPE effects in NSCs proliferation were shown by a significant increase in BrdU+ cells (representing labelled proliferating cells), while significant migration by GPEs in NSCs was presented by the wound closure rate, which was independent of cell proliferation