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Features of CKD include progressive retention of nitrogenous waste products in the blood (uremia), electrolyte imbalance, metabolic acidosis, and anemia (Duranton 2012)

[DOI] [PMC free article] [PubMed] [Google Scholar] 63.Bellei B., Migliano E., Picardo M

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In in vivo experiments, elevated circulating levels of TMAO in tumor-bearing mice lead to a significant increase in tumor volume, new blood vessel formation, and the quantities of VEGFA and CD31 [150]