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Eddy Pasquier (CNRS, France) and Prof
[DOI] [PMC free article] [PubMed] [Google Scholar] 12.Ramos-Nino M.E
Several NRF2 activators are currently undergoing clinical trials, including dimethyl fumarate, sulforaphane, bardoxolonemethyl, and omaveloxolone, whereas the pharmacokinetics issues and offtarget effects remain challenges [171, 172, 173, 174]
These clinical findings suggest that herbal formulations can complement or enhance conventional AD therapies, with lower side effects and improved safety profiles
