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The key role of histone acetylation in mGlu2 receptor regulation is also strengthened by the findings that chronic treatment with atypical antipsychotics down-regulates the expression of mGlu2 receptors in the mouse and human prefrontal cortex by increasing the binding of HDAC2 to the Grm2 promoter [39]

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J Neurosci Res 23 : 462466

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Proceedings of the National Academy of Sciences, 115(34), 86278632

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B., Dragsholt, C., Trostmann, A., Laier, E., and Larsen, H

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Furthermore, the results obtained in human AD brains provide a map of specific oxidized proteins, which could be useful as biomarkers for diagnostic and therapeutic purposes

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