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1), S52S59 (2016)

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Hormonal alterations Since stress has been described as a potential trigger for ME/CFS (422) and cause of symptom flare-ups (423, 424), it is likely that the HPA axis- the neurobiological stress system- may be implicated in ME/CFS (53, 425, 426), as well as abnormalities in growth hormone (GH) secretion and dysfunctional adrenergic metabolism (255)

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However, TRP2 not only facilitates these biochemical conversions but also provides protection against oxidative stress by elevating intracellular glutathione (GSH) levels and mitigating the deleterious effects of quinones, thereby averting DNA damage initiated by free radicals
