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6 ChenJ
doi: 10.1016/j.ejpn.2008.01.003 44


nc M, Gltekin F, Karaz E, Altunta , Deliba N

GPCRs are brought into an active conformational state by interacting with exogenous or endogenous agonists, which then affect the intracellular binding of G-proteins or arrestin proteins

Chronic activation of AMPK, due to a mutation in the gene encoding AMPK2, promotes ghrelin-dependent hyperphagia and obesity in mice and humans 193