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Description
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When the H6PD gene was knocked out in mice the pathology that resulted included fasting hypoglycemia, low hepatic glycogen content, increased sensitivity to insulin, and decreased negative feedback on the hypothalamic-pituitary-adrenal axis
Side effects can sometimes decrease over time, but we should seek medical attention if they are severe or long-lasting
Combined therapy (injections + ultrasound) maximizes metabolic activation
6 Hyperpigmentation and increased numbers of lentigines are features of Addisons disease
The third 2022 ECDP primary prevention algorithm concerns the last statin benefit group - patients with none of ASCVD, diabetes, or primary hypercholesterolemia, but with at least borderline 10-year ASCVD risk ( Figure 21-10 )
