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doi: 10.3390/nu12082263

GSH was well-tolerated and did not produce unexpected toxicity

In essence, the intermediate metabolite homocysteine is located at a metabolic crossroads, so it directly and indirectly affects all methyl and sulfur group metabolism occurring in the body

Although only a handful of Grx2 targets have been identified there are a number of mitochondrial proteins, which fulfill a multitude of functions that are known to undergo S-glutathionylation

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Maintaining optimal buffer conditions helps keep proteins in solution