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Furthermore, germline mutations in the genes encoding succinate dehydrogenase and fumarate hydratase result in increased levels of the TCA cycle metabolites fumarate and succinate that inhibit PHD activity [21, 93]

makeup smoother Micro-peeling visible renewed look Watch-outs: First-week tightness/dry patches (hydrate ) Sensitive skin- sting frequency reduce Sunscreen miss darkening/irritation Expert Opinions / Doctors Perspective (general guidance) Start low, go slow alternate nights, thin layer