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doi: 10.1007/s11695-016-2449-9

The secondary outcomes will be the serum vitamin B12 concentration (pg/ml), adverse events (description, moment of onset and resolution, intensity, cause, steps taken), adherence to treatment (measured at each patient visit via the number of vials used for patients in the oral arm, and the number of injections given in the intramuscular arm), quality of life (measured using the EuroQoL-5D questionnaire), and patient satisfaction and preferences

Maintain a Balanced Diet A balanced diet rich in B12-rich foods can help maintain optimal B12 levels

While caloric restriction alone often results in loss of both fat and muscle, AOD-9604 preferentially targets adipose tissue

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[Google Scholar] 450.Li Y, Ma Y, Yu J, Li C, Yu D, Dai R, et al