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Description
ROS/Ca 2+ signaling mediated by damaged mitochondria through MAMs may further affect chromatin homeostasis and gene transcription [266, 339]
Roy R, DAngiulli A
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Peroxisome proliferator activated receptor (PPAR) and PPAR gamma coactivator (PGC-1) induce carnitine palmitoyltransferase IA (CPT-1A) via independent gene elements
In rat cortical neuronal cultures, 9 -THC and cannabidiol, a nonpsychoactive component of Cannabis sativa, exhibited antioxidant activity and reduced glutamate toxicity by cannabinoid receptor-independent mechanism (Hamp-son et al., 1998)
its bidirectional dysregulation is implicated not only in gastrointestinal symptoms but may also help explain the high comorbidity between IBS and mood disorders
