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Many of these risk factors are inter-related, with one being a risk factor for the development of another

Metabolic remodeling during liver regeneration

[48] demonstrated the presence of Leu residues in the antioxidant collagen peptide sequence (GPLGLLGFLGPLGLS), which appears to play an important role in their ACE-inhibitory activity

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According to this theory, the first hit occurs due to the accumulation of lipids like triglycerides, followed by the second hit, where free radicals produced by cytokines and inflammatory mediators exacerbate the damage, exacerbating lipid metabolism abnormalities [20]