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10.1111/acn.12016 406 SorboniS

It has immune system effects

Less often, the color can appear on your neck, head, ears, or chest

Specifically, the expression of genes encoding TNF, TLR4, CD80, and CD86 molecules related to a proinflammatory phenotype were increased, while Il10 and Nos2 gene expression, which are known to inhibit antitumor T cell responses, were decreased (Figure 4D)

However, this option is only sometimes applicable

Demographics: Baseline characteristics reflected a real-world population (median age 64), with 35% of patients presenting with high-risk cytogenetics and 40% with soft-tissue plasmacytomas