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A female patient was reported to have cholestatic hepatitis in the setting of atorvastatin administration, but had pre-existing lupus erythematosus complicated by lupus nephritis
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observed that another enzyme involved in glycolysis, aldehyde dehydrogenase 2 (ALDH2), which also played an important role in oxidative stress and apoptosis, especially in MASLD patients and MCD-induced MASLD mice
Yousef MI, Salem MH, Kamel KI, at al
The downregulation of nicotinamide adenine dinucleotide phosphate and MAPK expression in turn increases reactive oxygen species (ROS) levels
