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The key cytosolic transcription factor, nuclear factor erythroid 2-related factor 2 (Nrf2) protein, regulates a wide range of genes for detoxification and antioxidant enzymes in response to xenobiotics and oxidative stress [391]
Ritchie SA, van den Hurk AF, Smout MJ et al (2018) Mission accomplished

These signals mediate cell induction and function, ensuring the homeostasis of the human immune system
Finding effective therapies that can delay the onset or progression of neurodegenerative diseases, especially AD and PD, is a primary goal and challenge for neuroscience research

[DOI] [PMC free article] [PubMed] [Google Scholar] 75.Phase I safety trial of intravenous ascorbic acid in patients with severe sepsis