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SMase-induced conformational changes appear to cause exposure of specific hidden regions of Apo B100 and increase surface hydrophobicity of LDL particles that are crucial for aggregation 66

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In summary, Madhugrit was found to have robust anti-diabetic, anti-inflammatory, and antioxidant properties which were assessed in various in vitro models and on a nematode model

Overall, this work has provided the first evidence that nuclear receptors modulate proteostasis through the remodelling of lipid metabolism

Spearman's rank correlation analysis was used to determine correlations

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