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(a) Concentration-dependence of Pde9a induction following 24-h exogenous propionate treatment in NRVMs in vitro

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Electrographic abnormalities are also seen, specifically epileptiform-like spikes in the hippocampus, neocortex, and basal ganglia, with discharges in the basal ganglia associated with measurable extrapyramidal behavioral abnormalities (194)