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Biochemical Mediators of Intestinal Chemical Barrier Function: Bile Acids The intestinal chemical barrier constitutes a critical defense mechanism against xenobiotic incursion, comprising bioactive agents including bile acids (BAs), gastric acid, digestive enzymes, mucins, and antimicrobial peptides

Encapsulation technologies (liposomal, nanoparticle) attempt to protect glutathione from proteolytic breakdown, potentially increasing bioavailability to 3050%

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Pharmacologically induced depletion of resident microglia with tamoxifen and diphtheria toxin prior to the induction of ischemic stroke in a mouse model resulted in a decreased infarct volume and levels of pro-inflammatory factors (Li et al., 2021)
