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PubMed Central , Linh, et al

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Although the combination of glucose metabolism and immunotherapy has more advantageous and clinical translation potential, it still faces the following challenges

Resulting placental insufficiency and overt clinical signs of PE do not manifest usually until the last pregnancy trimester (69) with a possibly rapid and unexpected progression from mild to severe PE (70)

Inhibition of vascular neointima hyperplasia by FGF21 associated with FGFR1/Syk/NLRP3 inflammasome pathway in diabetic mice

If symptoms persist, retesting or environmental testing might be helpful