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C., Zaretsky M

Cells derived from IGF1R / (complete deficiency of IGF1R) animals do not undergo malignant transformation when exposed to oncogenes (Sell et al., 1993

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McKnelly, K., Sokol, W., & Nowick, J

77,79,80 Further, oxidative stress is associated with preterm birth

However, COX-2 is inducible in many cells in response to certain mediators of inflammation (e.g., interleukin-1, tumor necrosis factor, lipopolysaccharide, mitogens, and reactive oxygen intermediates)