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FOXO3 activation has been shown to induce MAFbx and MuRF1 transcription, stimulate catabolism and cause muscle wasting [55, 56]

It is a component of enzymes responsible for DNA repair and removal of damaged cells

Nuclear receptors in nonalcoholic Fatty liver disease

Vinpocetine: An Unapproved Drug Sold as a Dietary Supplement

Plasma levels of endogenous and stable isotopelabeled l-carnitine, BB, and TMAO were determined by stable isotope dilution liquid chromatographytandem mass spectrometry (LC-MS/MS) in positive multiple reaction monitoring (MRM) mode as previously described (6) using a Shimadzu 8050 triple quadrupole mass spectrometer with ultra-HPLC interface

Synergistic effects of TCM formulations are particularly notable: JTD alleviates inflammatory cytokines, while AOB mitigates TMAO-induced cognitive impairment by enhancing synaptic plasticity and regulating synaptic proteins (Zhu et al., 2020