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10.1002/jor.20089 [DOI] [PubMed] [Google Scholar] Staresinic M., Sebecic B., Jadrijevic S., Suknaic S., Perovic D., Aralica G., et al

In addition, daratumumab has been conjugated to DOTA for radiolabeling with the alpha-emitter actinium-225 ( 225 Ac), showing potent CD38-positive tumor cell-killing in vitro and enhanced anti-tumor activity (~ 30-fold) in vivo without significant side effects [131]

Not necessarily, but careful evaluation and close monitoring are essential

Community protocols describing subcutaneous injection at 1-2 mg/day are self-reported and undocumented in peer-reviewed literature

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